miRNA description for miR-1246 |
miRNA accession |
miR-1246 |
Species |
Homo sapiens |
miR-1246 identified in exosomes derived from the following tissue/cell type |
Breast cancer cells [Exosomes]
|
20976003
|
Breast cancer cells [Exosomes]
|
20976003
|
Breast cancer cells [Exosomes]
|
20976003
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exosomes]
|
29472616
|
Colorectal cancer cells [Exomeres]
|
34887515
|
Colorectal cancer cells [Supermeres]
|
34887515
|
Mesenchymal stem cells [Extracellular vesicles]
|
34596354
|
Plasma [Exosomes]
|
29472616
|
Plasma [Exosomes]
|
29472616
|
Experiment description of studies that identified miR-1246 in exosomes |
1
|
Experiment ID | 333 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR Microarray |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 336 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF 10A |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 333 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR Microarray |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1435 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1436 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1437 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting miR-chip array |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1438 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry miR-chip array |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1439 |
Identified molecule | miRNA
|
Identification method | miR-chip array
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry miR-chip array |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1440 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 5 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qPCR |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1441 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 6 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qPCR |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1442 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 7 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qPCR |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 1443 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 8 |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 1444 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 5 |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 1445 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 6 |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
15
|
Experiment ID | 1446 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 7 |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
16
|
Experiment ID | 1447 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Colorectal cancer cells |
Sample name | HCT116 - Fraction 8 |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
17
|
Experiment ID | 3339 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34887515
|
Organism | Homo sapiens |
Experiment description | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets |
Authors | Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Colorectal cancer cells |
Sample name | DiFi |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Mass spectrometry ELISA RNA sequencing |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 3340 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
34887515
|
Organism | Homo sapiens |
Experiment description | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets |
Authors | Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Colorectal cancer cells |
Sample name | DiFi |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Mass spectrometry ELISA RNA sequencing |
EV-TRACK |
-
|
|
|
19
|
Experiment ID | 3202 |
Identified molecule | miRNA
|
Identification method | Small RNA sequencing
|
PubMed ID |
34596354
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p |
Authors | Lee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG. |
Journal name |
J Extracell Vesicles
|
Publication year | 2021 |
Sample | Mesenchymal stem cells |
Sample name | Adipose tissue-derived stem cells |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Flow cytometry Small RNA sequencing ddPCR |
EV-TRACK |
-
|
|
|
20
|
Experiment ID | 1448 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Plasma |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|
21
|
Experiment ID | 1449 |
Identified molecule | miRNA
|
Identification method | qPCR
|
PubMed ID |
29472616
|
Organism | Homo sapiens |
Experiment description | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 |
Authors | Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. |
Journal name |
Nat Commun
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Plasma |
Molecules identified in the study | miRNA |
Methods used in the study | qPCR |
EV-TRACK |
-
|
|
|